| Round | Opponent | Venue | Date | Home / Away | Result |
| 1 | Melbourne | Telstra Dome | Sunday 2 April (T) | Away | Won by 21 points |
| 2 | Fremantle | Subiaco | Saturday 8 April (N) | Away | Lost by 15 points |
| 3 | Sydney | Telstra Dome | Saturday 15 April (N) | Home | Lost by 7 points |
| 4 | Hawthorn | Telstra Dome | Friday 21 April (N) | Home | Lost by 32 points |
| 5 | Richmond | MCG | Friday 28 April (N) | Away | Lost by 8 points |
| 6 | Collingwood | MCG | Sunday 7 May | Home | Lost by 72 points |
| 7 | Essendon | MCG | Sunday 13 May | Home | Won by 33 points |
| 8 | St Kilda | MCG | Sunday 21 May | Home | Lost by 92 points |
| 9 | Adelaide | AAMI Stadium | Saturday 27 May | Away | Lost by 64 points |
| 10 | Port Power | Telstra Dome | Sunday 4 June | Home | Lost by 34 points |
| 11 | West Coast Eagles | Subiaco | Sunday 11 June | Away | Lost by 10 points |
| 12 | Kangaroos | Telstra Dome | Friday 23 June (N) | Away | Lost by 19 points |
| 13 | Brisbane | Gabba | Saturday 1 July (N) | Away | Lost by 15 points |
| 14 | Geelong | Telstra Dome | Saturday 8 July | Home | Lost by 65 points |
| 15 | Western Bulldogs | Telstra Dome | Sunday 16 July | Home | Lost by 30 points |
| 16 | Essendon | MCG | Saturday 22 July | Away | Drawn Match |
| 17 | Fremantle | Telstra Dome | Sunday 30 July | Home | Lost by 18 points |
| 18 | Melbourne | Telstra Dome | Saturday 5 August | Home | Won by 7 points |
| 19 | Hawthorn | MCG | Sunday 13 August | Away | Lost by 23 points |
| 20 | Richmond | Telstra Dome | Sunday 20 August | Home | Lost by 45 points |
| 21 | Collingwood | MCG | Sunday 27 August | Away | Lost by 44 points |
| 22 | Sydney | SCG | Sunday 3 September | Away | Lost by 92 points |
(Cached)